Synthesis, Characterization and Biological Activity of a Bidentate NS Schiff Base Containing S-Benzyl Dithiocarbazate and Its Zr(IV), Sn(II) Complexes
Md. Kudrat-E- Zahan
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Md. Faruk Hossen
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Rausan Zamir
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
Md. Ali Asraf *
Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh.
*Author to whom correspondence should be addressed.
Abstract
Zr (IV) and Sn (II) complexes were prepared with bidentate ligand, benzyl 2-(3-phenylallylidene) hydrazinecarbodithioate, derived from the condensation of S-benzyldithiocarbazate (SBDTC) with cinnamaldehyde and characterized by microanalysis, molar conductance and magnetic measurements, IR, electronic and ESI-MS studies. It was found that the ligand coordinated to the metal center through azomethine nitrogen and thiol sulfur atoms to form octahedral complexes with both the metal ions. The antimicrobial activities of the ligand and its complexes were investigated against the gram-positive and gram-negative bacteria and the fungus strain. The metal complexes showed strong activity than the free ligand.
Keywords: Schiff base, metal complex, antibacterial activity, antifungal activity.