Phytochemical Profile and Bioactive Compounds in Aqueous Seed Extract of Irvingia gabonensis: A GC-MS Analysis
Okari Karibo Amakiri *
Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Rivers State University, Nkpolu Oroworukwo, Port Harcourt, Nigeria.
Ezekwe Ahamefula Sunday
Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Rivers State University, Nkpolu Oroworukwo, Port Harcourt, Nigeria.
Wokocha Peter Gift
Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Rivers State University, Nkpolu Oroworukwo, Port Harcourt, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Irvingia gabonensis, commonly known as African mango, has gained significant attention for its nutritional and medicinal properties. This study investigated the phytochemical profile and identified bioactive compounds present in the aqueous seed extract of I. gabonensis using Gas Chromatography-Mass Spectrometry (GC-MS). The analysis revealed a variety of bioactive compounds, including fatty acids (e.g., palmitic acid, linoleic acid), terpenoids, alkaloids, and phenolic compounds. Key findings include the high peak area percentages of 2-Undecanone (31.3%) and 1,3-O-Benzylidine glyceryl-2-myric (15.4%), suggesting their significant bioactivity. The results indicate potential therapeutic applications in managing oxidative stress, inflammation, and metabolic disorders. Further studies, including in vivo evaluations, are recommended to explore these therapeutic potentials and establish safety profiles.
Keywords: Mango, nutritional properties, medicinal properties, oxidative stress, inflammation